逆轉錄酶（RTs）是用于從RNA模板生成互補DNA（cDNA）的酶，該過程稱為逆轉錄。 逆轉錄酶（RTs）使用RNA模板和與RNA 3'末端互補的短引物指導第一鏈cDNA的合成。 核苷逆轉錄酶抑制劑（NRTIs）阻斷逆轉錄酶（一種HIV酶）。 非核苷逆轉錄酶抑制劑（NNRTIs）結合并阻斷HIV逆轉錄酶。 HIV使用逆轉錄酶將其RNA轉化為DNA（逆轉錄）。 阻斷逆轉錄酶和逆轉錄阻止HIV復制。 Reverse transcriptases (RTs) are enzyme used to generate complementary DNA (cDNA) from an RNA template, a process termed reverse transcription. Reverse transcriptases (RTs) use an RNA template and a short primer complementary to the 3' end of the RNA to direct the synthesis of the first strand cDNA. Nucleoside reverse transcriptase inhibitors (NRTIs) block reverse transcriptase (an HIV enzyme). Non-nucleoside reverse transcriptase inhibitors (NNRTIs) bind to and block HIV reverse transcriptase. HIV uses reverse transcriptase to convert its RNA into DNA (reverse transcription). Blocking reverse transcriptase and reverse transcription prevents HIV from replicating.