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Ethambutol, (R,R)-

NMR下載 COA and HPLC MSDS下載
names：
2,2'-(ethane-1,2-diylbis(azanediyl))bis(butan-1-ol)
CAS號：
10054-05-4
MDL Number：
MF(分子式)： C10H24N2O2 MW(分子量)： 204.31
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文別名	Ethambutol, (R,R)-
英文別名	Ethambutol, (R,R)-; L-Ethambutol;
CAS號	10054-05-4
Inchi	InChI=1S/C10H24N2O2/c1-3-9(7-13)11-5-6-12-10(4-2)8-14/h9-14H,3-8H2,1-2H3
InchiKey	AEUTYOVWOVBAKS-UHFFFAOYSA-N
分子式 Formula	C10H24N2O2
分子量 Molecular Weight	204.31
溶解度Solubility
性狀	Solid powder
儲藏條件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

產品說明	Ethambutol, (R,R)-(CAS:10054-05-4):僅限應用于工業或者科學研究過程中非醫療目的，不應用于人類或動物的臨床診斷以及治過程療，該產品非藥用，非食用。
Introduction	Ethambutol, (R,R)- is a medication primarily used to treat tuberculosis. It is usually given in combination with other tuberculosis medications, such as isoniazid, rifampicin and pyrazinamide. It may also be used to treat Mycobacterium avium complex, and Mycobacterium kansasii.
Application1
Application2
Application3

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危險性	Warning
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備注

[1]Srivastava S, Gumbo T. Clofazimine for the treatment of Mycobacterium kansasii. Antimicrob Agents Chemother. 2018 May 29. pii: AAC.00248-18. doi: 10.1128/AAC.00248-18. [Epub ahead of print] PubMed PMID: 29844047.

[2]Vaghela JH, Nimbark V, Barvaliya M, Mehta H, Chavada B. Antituberculosis Drug-Induced Fixed Drug Eruption: A Case Report. Drug Saf Case Rep. 2018 May 21;5(1):23. doi: 10.1007/s40800-018-0086-z. PubMed PMID: 29785553; PubMed Central PMCID: PMC5962523.

[3] Lee JY, Han J, Seo JG, Park KA, Oh SY. Diagnostic value of ganglion cell-inner plexiform layer for early detection of ethambutol-induced optic neuropathy. Br J Ophthalmol. 2018 Apr 26. pii: bjophthalmol-2018-312063. doi: 10.1136/bjophthalmol-2018-312063. [Epub ahead of print] PubMed PMID: 29699978.

[4] Rezaei F, Haeili M, Fooladi AI, Feizabadi MM. High Resolution Melting Curve Analysis for Rapid Detection of Streptomycin and Ethambutol Resistance in Mycobacterium tuberculosis. Maedica (Buchar). 2017 Dec;12(4):246-257. PubMed PMID: 29610587; PubMed Central PMCID: PMC5879581.

[5] Fregonese F, Ahuja SD, Akkerman OW, Arakaki-Sanchez D, Ayakaka I, Baghaei P, Bang D, Bastos M, Benedetti A, Bonnet M, Cattamanchi A, Cegielski P, Chien JY, Cox H, Dedicoat M, Erkens C, Escalante P, Falzon D, Garcia-Prats AJ, Gegia M, Gillespie SH, Glynn JR, Goldberg S, Griffith D, Jacobson KR, Johnston JC, Jones-López EC, Khan A, Koh WJ, Kritski A, Lan ZY, Lee JH, Li PZ, Maciel EL, Galliez RM

6: Rahgozar N, Bakhshi Khaniki G, Sardari S. Evaluation of Antimycobacterial and Synergistic Activity of Plants Selected Based on Cheminformatic Parameters. Iran Biomed J. 2018 Mar 7. [Epub ahead of print] PubMed PMID: 29510602.7: Battini S, Mannava MKC, Nangia A. Improved Stability of Tuberculosis Drug Fixed-Dose Combination Using Isoniazid-Caffeic Acid and Vanillic Acid Cocrystal. J Pharm Sci. 2018 Jun;107(6):1667-1679. doi: 10.1016/j.xphs.2018.02.014. Epub 2018 Feb 17. PubMed PMID: 29462633.8: Sieniawska E, Sawicki R, Swatko-Ossor M, Napiorkowska A, Przekora A, Ginalska G, Augustynowicz-Kopec E. The Effect of Combining Natural Terpenes and Antituberculous Agents against Reference and Clinical Mycobacterium tuberculosis Strains. Molecules. 2018 Jan 15;23(1). pii: E176. doi: 10.3390/molecules23010176. PubMed PMID: 29342972.9: Patel N, Jagannath K, Vora A, Patel M, Patel A. A Randomized, Controlled, Phase III Clinical Trial to Evaluate the Efficacy and Tolerability of Risorine with Conventional Rifampicin in the Treatment of Newly Diagnosed Pulmonary Tuberculosis Patients. J Assoc Physicians India. 2017 Sep;65(9):48-54. PubMed PMID: 29313577.10: An H, Wang Z, Chen H, Wang T, Wang X, Liu L, Liu X, Xu J, He L, Zhang K, Zhang H, Liu X. Clinical efficacy of short-course chemotherapy combined with topical injection therapy in treatment of superficial lymph node tuberculosis. Oncotarget. 2017 Nov 18;8(66):109889-109893. doi: 10.18632/oncotarget.22492. eCollection 2017 Dec 15. PubMed PMID: 29299116; PubMed Central PMCID: PMC5746351.1

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