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Epiandrosterone Sulfate

NMR下載 COA and HPLC MSDS下載
names：
(3S,5S,9S,10S,13S,14S)-10,13-dimethyl-17-oxohexadecahydro-1H-cyclopenta[a]phenanthren-3-yl hydrogen sulfate
CAS號：
977-35-5
MDL Number：
MF(分子式)： C19H30O5S MW(分子量)： 370.504
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文別名	Epiandrosterone Sulfate
英文別名	Epiandrosterone Sulfate, Epiandrosterone, Epiandrosterone 16-bromo, Epiandrosterone 16 bromo,
CAS號	977-35-5
Inchi	InChI=1S/C19H30O5S/c1-18-9-7-13(24-25(21,22)23)11-12(18)3-4-14-15-5-6-17(20)19(15,2)10-8-16(14)18/h12-16H,3-11H2,1-2H3,(H,21,22,23)/t12-,13-,14?,15-,16-,18-,19-/m0/s1
InchiKey	ZMITXKRGXGRMKS-DDCNXBGYSA-N
分子式 Formula	C19H30O5S
分子量 Molecular Weight	370.504
溶解度Solubility
性狀	White to off-white crystalline powder.
儲藏條件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

產品說明	Epiandrosterone Sulfate(CAS:977-35-5 ):僅限應用于工業或者科學研究過程中非醫療目的，不應用于人類或動物的臨床診斷以及治過程療，該產品非藥用，非食用。
Introduction	Epiandrosterone Sulfate is a steroid hormone with weak androgenic activity. Epiandrosterone is naturally produced by the enzyme 5α-reductase from the adrenal hormone DHEA.
Application1
Application2
Application3

警示圖
危險性	Warning
危險性警示
安全聲明
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備注

[1]Sánchez-Guijo A, Oji V, Hartmann MF, Traupe H, Wudy SA. Simultaneous quantification of cholesterol sulfate, androgen sulfates, and progestagen sulfates in human serum by LC-MS/MS. J Lipid Res. 2015 Sep;56(9):1843-5[1]doi: 10.1194/jlr.D061499. Epub 2015 Aug 2. PubMed PMID: 26239050; PubMed Central PMCID: PMC4548788.

[2]Livshits G, Macgregor AJ, Gieger C, Malkin I, Moayyeri A, Grallert H, Emeny RT, Spector T, Kastenmüller G, Williams FM. An omics investigation into chronic widespread musculoskeletal pain reveals epiandrosterone sulfate as a potential biomarker. Pain. 2015 Oct;156(10):1845-51. doi: 10.1097/j.pain.0000000000000200. PubMed PMID: 25915148; PubMed Central PMCID: PMC4770329.

[3] Lewis JG, Bason LM, Elder PA. Production and characterization of monoclonal antibodies to dehydroepiandrosterone sulfate: application to direct enzyme-linked immunosorbent assays of dehydroepiandrosterone sulfate and androsterone/epiandrosterone sulfates in plasma. Steroids. 1996 Dec;61(12):682-7. PubMed PMID: 8987136.

[4] Dury AY, Ke Y, Gonthier R, Isabelle M, Simard JN, Labrie F. Validated LC-MS/MS simultaneous assay of five sex steroid/neurosteroid-related sulfates in human serum. J Steroid Biochem Mol Biol. 2015 May;149:1-10. doi: 10.1016/j.jsbmb.2015.01.006. Epub 2015 Jan 13. PubMed PMID: 25595042.

[5] Sánchez-Guijo A, Neunzig J, Gerber A, Oji V, Hartmann MF, Schuppe HC, Traupe H, Bernhardt R, Wudy SA. Role of steroid sulfatase in steroid homeostasis and characterization of the sulfated steroid pathway: Evidence from steroid sulfatase deficiency. Mol Cell Endocrinol. 2016 Dec 5;437:142-153. doi: 10.1016/j.mce.2016.08.019. Epub 2016 Aug 13. PubMed PMID: 27531568.

6: Mitamura K, Setaka M, Shimada K, Honma S, Namiki M, Koh E, Mizokami A. Determination of sulfates of androsterone and epiandrosterone in human serum using isotope diluted liquid chromatography-electrospray ionization-mass spectrometry. Biomed Chromatogr. 2005 Dec;19(10):796-801. PubMed PMID: 15954157.7: Higashi T, Shibayama Y, Kawasaki I, Shimada K. Determination of salivary 17-ketosteroid sulfates using liquid chromatography-electrospray ionization-mass spectrometry. J Pharm Biomed Anal. 2007 Apr 11;43(5):1782-8. Epub 2007 Jan 8. PubMed PMID: 17257796.8: PLAGER JE. THE BINDING OF ANDROSTERONE SULFATE, ETHIOCHOLANOLONE SULFATE, AND DEHYDROISOANDROSTERONE SULFATE BY HUMAN PLASMA PROTEIN. J Clin Invest. 1965 Jul;4

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